Oct 1, 2004 (CIDRAP News) – The National Institutes of Health (NIH) has awarded a $9.5 million grant to a Canadian firm that aims to develop an influenza vaccine that doesn’t rely on eggs.ID Biomedical of Vancouver, BC, announced on Sep 29 that it will use the grant to develop its cell culture–based influenza vaccine. Creating an alternative to the classic egg-based manufacturing process could speed development of vaccine, possibly improve vaccine effectiveness, and allow people with egg allergies to be vaccinated, according to a company press release.Shortened development time could prove very important in event of a flu pandemic, which is a growing concern with the spread of H5N1 avian influenza in Asia. The NIH grant will allow ID Biomedical to hold early-stage human trials of the new form of influenza vaccine.ID Biomedical’s Senior Vice President of Development Dr. Ronald Ellis said in the release, “We had shown a few years ago that our cell-derived vaccine manufactured by a prototype process was comparable in terms of safety and immunogenicity to our licensed egg-derived vaccine, Fluviral(R). This NIH grant enables IDB to continue this development toward a commercial process that should produce a vaccine with a safety and immunogenicity profile that fully meets the requirements for any influenza vaccine. Moreover, the grant also enables the development of and manufacturing process for a pandemic vaccine, should one be needed.”The new technology could let scientists grow a pandemic avian viral strain that might be harmful to eggs. As explained in the release, “There is currently a potential barrier to grow avian strains in eggs, since they have the potential to destroy the eggs.”The flu vaccine program at ID Biomedical will include development of injectable and intranasal influenza vaccines based on its cell-culture production technology.ID Biomedical supplies over 75% of influenza vaccine to the Canadian public market.See also:ID Biomedical press releasehttp://www.bctechnology.com/scripts/display_news.cfm?id=19256
AREGENTINA fought back to beat Croatia 3-2 and win the Davis Cup for the first time in a dramatic final in Zagreb.Croatia led 2-1 going into the final day and looked on course for their second title when Marin Cilic led Juan Martin del Potro by two sets to love.However, del Potro staged a remarkable comeback to win 6-7(4-7), 2-6, 7-5, 6-4, 6-3 in four hours 53 minutes.Federico Delbonis then swept past Ivo Karlovic 6-3, 6-4, 6-2 in the decisive fifth contest to clinch victory.Argentina had lost in four previous finals but, roared on by a vociferous 1500-strong group of travelling fans that included 1986 World Cup winner Diego Maradona, the visitors secured a stunning win.del Potro set the victors on their way from a seemingly desperate situation at two-sets down to world number six Cilic.The victory capped a terrific year which has seen the 28-year-old return from four wrist surgeries to win Olympic silver and beat the likes of Novak Djokovic, Stan Wawrinka and, in the quarter-finals of the Davis Cup, Andy Murray.“This was an emotionally exhausting match and one of the biggest wins of my career,” said del Potro.“Thanks to all those who prevented me from retiring; I was very close to never playing again and, well, here I am.”Argentina captain Daniel Orsanic added: “His comeback is the comeback of history, his comeback today was the comeback of the Davis Cup.“He’s a genius. His heart is so big.”Delbonis is ranked 21 places below Karlovic at 41 in the world but brilliantly returned the 6ft 11in Croat’s huge serve.“He was on top of every ball,” said Orsanic. “He played a perfect match. I’m surprised, in a good way. I thought he couldn’t win so easy.”(BBC Sport)
13 Top nine Premier League free transfers of the decade 10. Diego Simeone (Atletico Madrid manager): 4 trophies – League titles won: 1 x LaLiga; Domestic cup competitions won: 1 x Copa Del Rey; European competitions won: 2 x Europa League 13 MONEY How Arsenal could line up in Arteta’s first official game in charge – Ozil return? 13 13 13 7. Unai Emery (Arsenal manager): 7 trophies – League titles won: 1x Ligue 1; Domestic cup competitions won: 2 x Coupe De France, 1 x Coupe de la Ligue; European competitions won: 3 x Europa League 5. Max Allegri (Juventus manager): 9 trophies – League titles won: 5 x Serie A; Domestic cup competitions won: 4 x Coppa Italia Forbes list reveals how much Mayweather, Ronaldo and Messi earned this decade RANKED silverware 10. Didier Deschamps (France manager): 6 trophies – League titles won: 1 x Ligue Un; Domestic cup competitions won: 4 x Coupe de la Ligue; International trophies won: 1x World Cup 13 Tottenham predicted XI to face Brighton with Mourinho expected to make big changes 13 1. Jose Mourinho (Man United manager): 17 trophies – League titles won: 3 x Premier League, 2 x Serie A, 1 x LaLiga; Domestic cup competitions won: 4 x League Cup, 1 x FA Cup, 1 x Coppa Italia, 1 x Copa Del Rey; European competitions won: 2 x Champions League, 2 x Europa League/UEFA Cup highlights England’s most successful clubs of the past decade, according to trophies won 3. Carlo Ancelotti (Napoli): 10 trophies – League titles won: 1 x Serie A, 1 x Premier League, 1 x Ligue Un, 1 x Bundesliga; Domestic cup competitions won: 1 x Coppa Italia, 1 x FA Cup, 1 x Copa del Rey; European competitions won: 3 x Champions League Every Championship club’s best signing of the decade, including Taarabt and Dack 13 13 It seems to be a widely-held view within football that Pep Guardiola is the best manager in the game.He has been credited with revolutionising the sport during his glittering four year-spell in charge of Barcelona, while he enjoyed success in Germany with Bayern Munich before heading to England to take charge of Manchester City in 2016 where he transformed the way City play.Jose Mourinho, meanwhile, seems to be having a tough time at rivals Man United despite being a serial winner throughout his career.So who can lay claim to be the best in the business? Here, talkSPORT.com looks at the current managers with the best trophy record in European football.*Only titles won in the top-five leagues in Europe (the Premier League, Bundesliga, LaLiga, Serie A and Ligue 1) are counted, as well as major domestic cup and European competitions, which is why, for example, Jose Mourinho’s two league crowns and one Portuguese Cup are not included. Excluded are the Super Cup, the Community Shield and each league’s equivalent as well as the Club World Cup – Champions League winners are parachuted straight into a semi-final against a questionable standard of opposition. 6. Marcello Lippi (China manager): 8 trophies – Marcello Lippi won the World Cup with Italy in 2006 =13th Jurgen Klopp (Liverpool manager): 3 trophies 13 Tottenham v Brighton LIVE: talkSPORT commentary and team news for Boxing Day opener gameday 13 2. Pep Guardiola (Man City manager): 14 trophies – League titles won: 3 x LaLiga, 3 x Bundesliga, 1x Premier League; Domestic cup competitions won: 2 x Copa Del Rey, 2 x DFB Pokal, 1x EFL Cup; European competitions won: 2 x Champions League ALTERED 13 =7. Rafael Benitez (Newcastle manager): 7 trophies – League titles won: 2 x LaLiga; Domestic cup competitions won: 1 x FA Cup, 1 x Coppa Italia; European trophies won: 1 x Champions League, 2x Europa League/UEFA Cup Getty Football news 13. Mauricio Pellegrini (West Ham manager): 3 trophies – League titles won: 1 x Premier League; Domestic cup competitions won: 2 x League Cup =5. Roberto Mancini (Italy manager): 9 trophies – League titles won: 3x Serie A, 1x Premier League; Domestic cup competitions won: 4x Coppa Italia, 1X FA Cup How the Premier League table could change after the Boxing Day fixtures Every current Premier League club’s best kit from the past decade =10. Luis Enrique (Spain manager): 6 trophies – League titles won: 2 x LaLiga; Domestic cup competitions won: 3 x Copa Del Rey; European competitions won: 1 x Champions League NEW ERA smart causal possible standings 13 impact Best clips, calls and talkSPORT moments of 2019, feat Hearn, McCoist and more
Robredo should’ve resigned as drug czar after lack of trust issue – Panelo Robredo: True leaders perform well despite having ‘uninspiring’ boss PLAY LIST 02:49Robredo: True leaders perform well despite having ‘uninspiring’ boss02:42PH underwater hockey team aims to make waves in SEA Games01:44Philippines marks anniversary of massacre with calls for justice01:19Fire erupts in Barangay Tatalon in Quezon City01:07Trump talks impeachment while meeting NCAA athletes02:49World-class track facilities installed at NCC for SEA Games Photo by Tristan Tamayo/INQUIRER.netThe NCAA on Wednesday imposed one-game suspensions on San Beda head coach Boyet Fernandez, Red Lions Robert Bolick and Clint Doliguez, and College of St. Benilde wingman Carlo Young.The three players were involved in an in-game scuffle late in the Red Lions 72-58 win on Tuesday.ADVERTISEMENT Ethel Booba on hotel’s clarification that ‘kikiam’ is ‘chicken sausage’: ‘Kung di pa pansinin, baka isipin nila ok lang’ LATEST STORIES Hotel says PH coach apologized for ‘kikiam for breakfast’ claim Celebrity chef Gary Rhodes dies at 59 with wife by his side Neymar calls Barca president a ‘joke’ Young launched for a takedown that brought Bolick to the floor, igniting a series of ejections that saw Bolick and Doliguez get thrown out with 2:28 remaining in the game.Fernandez, meanwhile, was suspended for his second infraction of “disrespecting game officials.”FEATURED STORIESSPORTSSEA Games: Biñan football stadium stands out in preparedness, completionSPORTSPrivate companies step in to help SEA Games hostingSPORTSBoxers Pacquiao, Petecio torchbearers for SEA Games openingBolick was also given a warning by NCAA commissioner Bai Cristobal for the aforementioned offense.The suspension took Bolick out of the running for any individual awards including the Most Valuable Player plum. The San Beda star was sixth in the MVP rae. Celebrity chef Gary Rhodes dies at 59 with wife by his side MOST READ NATO’s aging eye in the sky to get a last overhaul The San Beda mentor launched a tirade after the game Tuesday questioning the disqualifying foul on Bolick.“I don’t want to insinuate things. I don’t want to speculate, but it’s a won game already, and then that incident happened and they penalized the other team that did not start it,” he said. “If they want us to lose ball games, then let us lose that ball game in a proper way,” Fernandez told the media.Sports Related Videospowered by AdSparcRead Next Don’t miss out on the latest news and information. Lacson: SEA Games fund put in foundation like ‘Napoles case’ Trump signs bills in support of Hong Kong protesters View comments
About the authorCarlos VolcanoShare the loveHave your say Barcelona coach Valverde delighted with Levante rout: Very different to last yearby Carlos Volcano10 months agoSend to a friendShare the loveBarcelona coach Ernesto Valverde was delighted with their 5-0 win at Levante.Lionel Messi shone for the Catalans as the Argentine bagged three goals and provided two assists.”We are happy because last year we played here and conceded five after a whole season without losing,” Valverde said.”That was only a few months ago, they are having a great season and they keep showing that.”We remembered last year and we managed to put it behind us and leave with a clean sheet.”Levante started well on Sunday but ultimately fell short and Valverde says he expected the game to begin as it did.”They started as we imagined,” he said.”We had to change the setup based on the casualties we had so it was difficult for us and they squeezed us.”They’re able to score and dangerous when they counterattack but we had the fortune of opening the score.”
TagsTransfersAbout the authorPaul VegasShare the loveHave your say Real Madrid competing with Man Utd for Napoli defender Koulibalyby Paul Vegas10 months agoSend to a friendShare the loveReal Madrid are competing with Manchester United for Napoli defender Kalidou Koulibaly.United have eyed the Napoli defender since the summer, with former manager Jose Mourinho viewing him as the man to fix his leaky defence, and they made a world-record bid for him.But Il Mattino says they could face a serious rival for his signature.Koulibaly has grown into one of the finest defenders on the continent over the last season and a half.And that has led to Real eyeing him as a potential January addition as they look to recover from their shaky start to the season.Napoli are believed to be willing to accept a bid of around £90million for the Senegalese star.
About the authorPaul VegasShare the loveHave your say Man Utd boss Solskjaer on away form: Do I look concerned?by Paul Vegasa month agoSend to a friendShare the loveManchester United boss Ole Gunnar Solskjaer insists he isn’t worried by their poor away form ahead of the trip to West Ham. They have not won away from Old Trafford in eight games since the sensational 3-1 victory at Paris Saint-Germain in early March, losing five of them.”Why should we coaches be concerned?” he said. “We’re looking forward to things, looking for solutions. I’ve never been concerned about anything really. I don’t walk around and worry about things. I’m looking what we can do to improve. I’ve never been a worrier.”I think we should have won at Southampton, I think we should have won the Wolverhampton one. Both should be wins.”It’s still the same size pitch, green with white lines, some fans. You’ve got to block out the mental part and play as you would in the park.”Last year we were lucky to beat them (West Ham). It will be a good test again for us. We’ve had two clean sheets now, and that will give the defenders confidence. If we can keep a clean sheet, it will be easier for the strikers. You don’t have to score twos, threes and fours every time.”
Twitter/@McMurphyESPNA number of names have emerged as possible candidates to take over the Miami Hurricanes, including alumni like Mario Cristobal and Rob Chudzinski, and former ‘Canes coach Butch Davis. While the prevailing thought is that Miami may struggle to draw a huge name, ESPN college football insider Brett McMurphy has heard that one prominent coach with South Florida ties may be interested: Texas head coach Charlie [email protected] on charlie strong pic.twitter.com/E69TeTfyXg— Chris Bennett (@chrisgb00) October 26, 2015Strong is only in year two at Texas, and seems to be picking up some steam after a very rocky start to 2015, so this would seem to be a hard sell. However, he knows the landscape well, spending a number of years as an assistant coach at Florida. Strong would probably be the splash hire that Miami fans may want, but it is hard to see him leaving Austin right now.
zoomImage Courtesy: Brittany Ferries France-based shipping company Brittany Ferries has confirmed the charter of two new cruise-ferries to serve its long-haul UK to Spain routes.To be chartered from Swedish shipping company Stena RoRo, the ships will be built at the Avic International Weihai shipyard in China, with the first arriving in 2021.The latest investment comes after work began this spring on a brand new LNG cruise ferry called Honfleur to serve the Portsmouth – Caen crossing. Like Honfleur, which arrives in 2019, both ships announced today will be registered under the French flag and will be crewed by French seafarers.“Together the three ships will spearhead a wide-ranging, five-year fleet-renewal and modernisation programme worth around GBP 400m,” Brittany Ferries said in a statement.Portsmouth is Brittany Ferries’ UK hub and will serve as the base for both ships. Upon arrival they ships cater for an ever-increasing demand for long-haul ferry travel to Spain. In 2017 the company, operated 844 sailings on routes from Portsmouth, Poole and Plymouth to Santander (Cantabria) and Bilbao (Basque Country), carrying 331,000 passengers and 150,000 cars. That was around 80 percent more than ten years earlier, as informed by Brittany Ferries.“Spain is by far the most popular foreign destination for UK holidaymakers, and we have seen significant growth in demand. Post-Brexit, we expect this to continue and today’s announcement is a clear statement of intent. As well as passenger traffic, we believe that an increase in freight capacity will open the door to more hauliers seeking direct access between Britain and the Iberian peninsula,” Jean-Marc Roué, Brittany Ferries’ president, commented.With a length of 215 meters and a width of 27.8 meters, the new 42,200-ton vessels will be the longest in Brittany Ferries’ fleet. The new ships, belonging to Stena RoRo’s new generation of ‘E-Flexer’ vessels, will be gas-ready. They will have around 300 cabins that will cater for approximately 1,000 passengers, according to the company.The announcement follows the launch of the first ever direct ferry service linking Ireland with Spain in April. Brittany Ferries’ Connemara made its first call into Santander from Cork on May 9, 2018.